Custom Peptides
Cayman Chemical SureLIghtPerCP CynIn 5 5 10mg
SureLight™ PerCP Cyanine 5.5 is a fluorescent probe used in protein detection Excitation max. λ: 496 nm Emission max. λ: 517 nm Uses: Custom antibody labeling, fluorescence-activated cell sorting, flow cytometry, Luminex, and T cell labeling
Cayman Chemical D-TetrahydropalmatIn 10mg
A tetrahydroberberine alkaloid; reverses apomorphine-induced inhibition of dopaminergic firing in the SNC in paralyzed rats at 32 mg/kg
Cayman Chemical CrostIdetrIfluoroacetAT s 10mg
A peptide substrate for Akt; corresponds to the amino acid sequence of GSK3 that surrounds the serine residue phosphorylated by RSK1 or p70S6K; also a substrate for SGK3
Cayman Chemical EIcosapentaenoylLcarnItIn 10mg
A long-chain acylcarnitine; levels are increased in the eyes of mice fed a diet high in n-3/n-6 PUFAs, but not in mice fed normal diet, in a mouse model of myopia induced by out-of-focus lenses
Cayman Chemical ConIferyl Ferulate 10mg
A monolignol conjugate; active against B. subtilis and S. aureus; scavenges DPPH radicals (EC50 = 3.6 UG/ml) and inhibits GST (IC50 = 0.3 µM for the human placental enzyme) in cell-free assays; reduces cytotoxicity induced by Aβ40 in PC12 cells at 10 and 50 UG/ml
Cayman Chemical D-Celopentaose 10mg
An oligosaccharide; has been used as a synthetic acceptor co-substrate to characterize the binding domains and enzyme kinetics of the E. coli pEtN transferase BcsG; has been used a substrate for a synthetic receptor designed to solubilize polysaccharides for use in tissue engineering and biological applications
Cayman Chemical SurfenhydrochlorIde 10mg
An antagonist of cell surface glycosaminoglycans; binds to heparin, dermatan sulfate, heparan sulfate, and chondroitin sulfate and prevents heparin-induced inhibition of Factor Xa in cell-free assays; inhibits FGF2 binding to CHO cells (IC50 = 5 µM) and FGF2-induced tube formation by primary mouse endothelial cells; inhibits neural differentiation and increases pluripotency in mESCs at 5 µM
Cayman Chemical NS 8593hydrochlorIde 10mg
An inhibitory gating modifier of SK channels (Kds = 0.42, 0.6, and 0.73 μM for SK1, SK2, and SK3, respectively, in the presence of calcium); decreases the calcium sensitivity of SK channels; selective for SK channels over IK and BK potassium channels at 10 μM; induces relaxation of potassium- or acetylcholine chloride-precontracted isolated tracheal rings from wild-type mice (IC50s = 8.9 and 39.8 μM, respectively) or from mice in an ovalbumin-induced model of allergic asthma (IC50s = 16.4 and 32.2 μM, respectively); inhibits aerosolized acetylcholine chloride-induced increases in respiratory system resistance in mice when administered as an aerosol at 500 μM; decreases the duration of burst-pacing-induced atrial fibrillation in normotensive and spontaneously hypertensive rats at 5 mg/kg
Cayman Chemical Pentadecnoyl-L-carnItInch 10mg
A CB receptor agonist (EC50s = 3.7 and 3.2 µM for CB1 and CB2 receptors, respectively, in a cAMP modulation assay); a 5-HT1A and 5-HT1B agonist (EC50s = 9.6 and 9.3 µM, respectively); a histamine H1 and H2 antagonist (EC50s = 10.9 and 6.1 µM, respectively); inhibits T cell proliferation in an SAg primary human cell system; reduces CCL2 levels in an Mphg primary human cell system
Cayman Chemical TatM2NXtrIfluoroACTAte sa 10mg
A peptide TRPM2 antagonist; inhibits hydrogen peroxide-induced calcium influx in HEK293 cells expressing human TRPM2 from 25-100 µM; reduces brain infarct volume in male mice in a model of MCAO-induced stroke at 20 mg/kg pre- or 3-hours-post occlusion
Cayman Chemical ThonzonIumbromIde 10mg
A quaternary ammonium-containing cationic surfactant with diverse biological activities; an inhibitor of F. tularensis AcpB (Ki = 0.59 µM) and C. albicans V-ATPase (EC50 = 69 µM); inhibits osteoclastogenesis RANKL-induced osteoclastogenesis in BMDMs; inhibits bone resorption by mature osteoclasts at 100 and 200 nM; prevents LPS-induced bone loss in a calvarial osteolytic mouse model at 5 mg/kg per day; induces mortality in C. oncophora, O. ostertagi, H. contortus, and T. circumcincta (EC50s = 4.5, 10.8, 5.1, and 6.7 µM, respectively) but is cytotoxic to HEK293 and RAW 264.7 cells (CC50s = 9.2 and 5.7 µM, respectively)