Custom Peptides
Cayman Chemical 3-O-methyl-L-DOPAhydrate 10mg
An active metabolite of L-DOPA; inhibits L-DOPA-induced neuroprotection in rat primary mesencephalic dopaminergic neurons at 10 and 100 µM
Cayman Chemical 4ChLRomethcathInonhydroc 10mg
An analog of methcathinone that has a chlorine atom inserted at the 4 position of the phenyl ring; intended for forensic and research applications
Cayman Chemical BIvalIrudIn 10mg
A thrombin inhibitor (Kis = 2.56 and 1.84 nM for α- and ζ-thrombin, respectively); selective for α- and ζ-thrombin, lacking activity at trypsin and γ-thrombin at a >1,000-fold excess; inhibits α-thrombin-stimulated activation of the clotting factors Factor X, Factor V, and prothrombin in contact-activated plasma; reduces platelet deposition in a rat carotid endarterectomy model in a dose-dependent manner
Cayman Chemical -MethylamIno-L-AlnInhydr 10mg
A neurotoxic non-proteinogenic amino acid; cytotoxic to mouse primary cortical neurons at 3 mM; stimulates release of glutamate and induces oxidative stress in the same cells at 3 mM; enhances amyloid-β (25-35)-induced neuronal cell death in mouse primary cortical neurons at 0.1 mM; induces wet-dog shakes, rigidity, and clonic convulsions in rats at 500 UG/animal; induces parkinsonism in cynomolgus monkeys; has been found in commercial seafood
Cayman Chemical BrasIcasterol 10mg
A phytosterol; inhibits recombinant sterol Δ24-reductase (Ki = 42.7 μM) in vitro; increases accumulation of desmosterol and inhibits cholesterol formation in HL-60 cells in a dose-dependent manner; inhibits the hemolytic activity of pneumolysin from S. pneumoniae
Cayman Chemical D-threo-PPMPhydrochlorIde 10mg
A GlyCer synthetase inhibitor; an inhibitor of MDCK cell growth in vitro (70% reduction at 20 µM); an inhibitor of DNA synthesis at 3 µM
Cayman Chemical Amodaqun 10mg
A prodrug form of N-desethyl amodiaquine; active against several strains of P. falciparum in vitro (EC50s = 0.23-0.52 nM) and exhibits a synergistic effect when used in combination with N-desethyl amodiaquine; dose-dependently inhibits development of parasitemia in a mouse model of P. berghei infection
Cayman Chemical KN-93hydrochlorIde 10mg
A selective inhibitor of CaMKII, competitively blocking CaM binding to the kinase (Ki = 370 nM); inhibits histamine-induced aminopyrine uptake in parietal cells (IC50 = 300 nM)
Cayman Chemical CalmIdazolIumchlorIde 10mg
An inhibitor of CaM, inhibiting CaM-dependent phosphodiesterase and CaM-induced activation of erythrocyte calcium-transporting ATPase (IC50 = 0.15 and 0.35 µM, respectively); also inhibits an array of calcium-transporting ATPases (IC50 = 2.1 and 2.9 µM, respectively)
Cayman Chemical ADBPINCA pentnoIc ACD met 10mg
An expected compound produced by phase I metabolism of ADB-PINACA in vivo, based on the metabolism of comparable alkylindole CBs
Cayman Chemical SemI-synthetIc FerutInIn 10mg
A plant-derived ester of a sesquiterpenic alcohol that acts as an agonist for ERα (IC50 = 33.1 nM) and an agonist/antagonist for ERβ (IC50 = 180.5 nM); demonstrates ionophorectic properties, increasing calcium permeability of lipid bilayer membranes, mitochondria, thymocytes, sarcoplasmic reticulum, and liposomes at 1-50 µM
Cayman Chemical GInsenosIde Rd 10mg
A protopanaxadiol that has diverse in vitro and in vivo effects, including cardioprotective, neuroprotective, and anti-inflammatory actions
Cayman Chemical MEAIhydrochlorIde 10mg
A derivative of MMAI, a psychoactive aminoindane that has been identified in recreational drug mixtures; intended for forensic and research purposes
Cayman Chemical 5-MAPDBhydrochlorIde 10mg
An entactogen belonging to the amphetamine and the phenethylamine classes that is structurally related to the MDA analog, 5-APDB, and MDMA; intended for forensic and research purposes
Cayman Chemical CInabarInIc AcId 10mg
An agonist of mGluR4 and active metabolite of 3-hydroxyanthranilic acid; selectively induces inositol phosphate production in HEK293 cells expressing mGluR4 over HEK293 cells expressing mGluR1, mGluR2, mGluR5, mGluR6, mGluR7, or mGluR8 at 100 µM; inhibits DAAO in a cell-free assay (IC50 = 1.37 µM); increases levels of ROS and induces apoptosis in primary mouse thymocytes at 30 µM